In the ever-evolving landscape of endovascular thrombectomy (EVT) devices, safety and efficacy improvements are paramount. These innovations aim to enhance recanalization for large vessel occlusion strokes while also tackling medium and distal vessel occlusions.

To ensure objective comparative analyses, a crucial need arises: the development of in-vitro safety metrics for these novel EVT devices.

In a recent study, researchers made a noteworthy discovery. Withdrawal of an unsheathed stent-retriever from the middle cerebral artery led to significant deflection of the internal carotid artery terminus in an in-vitro stroke model. The extent of deflection varied in different planes and depended on the stent-retriever design. This finding underscores the importance of further investigations to explore predictors and the potential impact of this deflection on stroke treatment outcomes